bioRxiv：生物预印本服务器简介和发布指南

https://www.biorxiv.org/

什么是bioRxiv

About bioRxiv

https://www.biorxiv.org/about-biorxiv

bioRxiv发音为bio-archive，提供是生命科学免费的末发表预印本在线存储和发布服务。它由非营利的研究和教育机构冷泉港实验室运维。当在bioRxiv上发布预印本后，作者可以使研究成果对整个科研群体可用，并在投稿前收到草稿的反馈意见。

bioRxiv (pronounced “bio-archive”) is a free online archive and distribution service for unpublished preprints in the life sciences. It is operated by Cold Spring Harbor Laboratory, a not-for-profit research and educational institution. By posting preprints on bioRxiv, authors are able to make their findings immediately available to the scientific community and receive feedback on draft manuscripts before they are submitted to journals.

文章在网上发布之前，不会被同行评审、编辑或排版。但是，所有文章都要经过一个基本的筛选过程，筛选出具有攻击性和/或非科学性的内容，以及可能造成健康或生物安全风险的材料，并检查是否有抄袭行为。冷泉港实验室对一篇文章的方法、假设、结论或科学质量的认可，并不意味着它出现在Biorxiv中。文章可以在提交杂志之前或同时发布，但如果已被杂志接受发布，则不应发布。

Articles are not peer-reviewed, edited, or typeset before being posted online. However, all articles undergo a basic screening process for offensive and/or non-scientific content and for material that might pose a health or biosecurity risk and are checked for plagiarism. No endorsement of an article’s methods, assumptions, conclusions, or scientific quality by Cold Spring Harbor Laboratory is implied by its appearance in bioRxiv. An article may be posted prior to, or concurrently with, submission to a journal but should not be posted if it has already been accepted for publication by a journal.

在期刊正式接受文章之前，作者可以随时通过点击作者区域内的“提交修订”来提交文章的修订版本。一旦发布到biorxiv上，文章就可以引用，因此无法删除。

Authors are free to submit a revised version of an article at any time prior to its formal acceptance by a journal by clicking “Submit a Revision” within the Author Area. Once posted on bioRxiv, articles are citable and therefore cannot be removed.

包括的范围

SCOPE

Biorxiv接受涵盖生命科学研究各个方面的文章预印本。在发布文章时，作者将其分配到以下类别之一：

bioRxiv accepts preprints of articles covering all aspects of research in the life sciences. When posting an article, the author assigns it to one of the following categories:

• 动物行为与认知(Animal Behavior and Cognition)
• 生物化学(Biochemistry)
• 生物工程(Bioengineering)
• 生物信息学(Bioinformatics)
• 生物物理学(Biophysics)
• 癌症生物学(Cancer Biology)
• 细胞生物学(Cell Biology)
• 临床试验(Clinical Trials)
• 发育生物学(Developmental Biology)
• 生态学(Ecology)
• 流行病学(Epidemiology)
• 进化生物学(Evolutionary Biology)
• 遗传学(Genetics)
• 基因组学(Genomics)
• 免疫学(Immunology)
• 微生物学(Microbiology)
• 分子生物学(Molecular Biology)
• 神经科学(Neuroscience)
• 古生物学(Paleontology)
• 病理学(Pathology)
• 药理学与毒理学(Pharmacology and Toxicology)
• 生理学(Physiology)
• 植物生物学(Plant Biology)
• 科学传播与教育(Scientific Communication and Education)
• 合成生物学(Synthetic Biology)
• 系统生物学(Systems Biology)
• 动物学(Zoology)

物理科学、数学或社会科学中的文章只有在与生命科学有直接关联的情况下才应该发表在Biorxiv上。与生命科学无关的这些领域的文章应该发布在如arxiv服务器上，biorxiv的目的是专业领域的细划和补充。

Articles in the physical sciences, mathematics, or social sciences should only be posted on bioRxiv if they have direct relevance to the life sciences. Articles in these areas that are not relevant to life sciences should instead be posted on servers such as arXiv, which bioRxiv is intended to complement.

文章类别

ARTICLE CATEGORIES

Biorxiv中的文章分为新结果、证实性结果或矛盾结果。新的结果描述了一个领域的进步。证实性结果在很大程度上重复和证实了先前发表的工作，而矛盾的结果在很大程度上重复了先前发表的工作中使用的实验方法，但结果矛盾和/或不支持先前的结论。
支持它。

Articles in bioRxiv are categorized as New Results, Confirmatory Results, or Contradictory Results. New Results describe an advance in a field. Confirmatory Results largely replicate and confirm previously published work, whereas Contradictory Results largely replicate experimental approaches used in previously published work but the results contradict and/or do not support it.

评论

COMMENTING

读者可以在关于Biorxiv的文章中添加公开评论。评论要适度，以确保它们符合正常的专业谈话标准。读者也可以直接联系作者。

Readers may add public comments to articles on bioRxiv. Comments are moderated to ensure they conform to the standards of normal professional discourse. Readers are also free to contact authors directly.

分发条款

TERMS OF DISTRIBUTION

作者保留版权，并从几个分发/重用选项中选择使文章可用的选项（CC-BY, CC-BY-NC, CC-BY-ND, CC-BY-NC-ND, CC0,或不重用）。通过在bioRxiv上发布，作者明确同意对他们的作品进行文本挖掘（例如，通过搜索引擎或研究人员）。

Authors retain copyright and choose from several distribution/reuse options under which to make the article available (CC-BY, CC-BY-NC, CC-BY-ND, CC-BY-NC-ND, CC0, or no reuse). By posting on bioRxiv, authors explicitly consent to text mining of their work (e.g., by search engines or researchers).

Biorxiv保留鉴定和删除任何含有剽窃材料或描述实验工作的工作的权利，这些实验工作不符合使用动物或人类受试者进行研究的相关伦理标准。

bioRxiv reserves the right to identify and remove any articles that contain plagiarized material or describe experimental work that is not performed in accordance with the relevant ethical standards for research using animals or human subjects.

杂志预印本政策

JOURNAL PREPRINT POLICIES

大多数研究期刊允许在出版前在预印本服务器（如bbioRxiv）上发表文章。可以在维基百科和SHERPA/RoMEO上找到期刊政策列表。作者应该在发布bioRxiv之前查阅这些列表和其他信息来源。

Most research journals allow posting on preprint servers such as bioRxiv prior to publication. A list of journal policies can be found on Wikipedia and SHERPA/RoMEO. Authors should consult these lists and other sources of information before posting on bioRxiv.

出版

PUBLICATION

Biorxiv通常会在期刊出版后的几周内自动添加到已出版版本的链接。有时，由于标题或作者发生变化或其他意外事件，不进行匹配。如果链接未出现，请等待2-3周后再联系Biorxiv员工。

bioRxiv will usually automatically add a link to the published version within several weeks of journal publication. On occasion a match is not made because the title or authors have changed or due to other contingencies. Please wait 2-3 weeks before contacting bioRxiv staff should the link not appear.

隐私政策：收集和使用个人数据

PRIVACY POLICY: COLLECTION AND USE OF PERSONAL DATA

冷泉港实验室致力于保护bioRxiv提交系统和网站的作者、预印本服务器附属公司和其他用户的隐私。阅读完整的隐私政策见链接 http://cshlp.org/misc/preprints_privacy_policy/ 。

Cold Spring Harbor Laboratory is committed to protecting the privacy of authors, preprint server Affiliates, and other users of the bioRxiv submission system and website. Click to read the full Privacy Policy.

提交指南

Submission Guide

https://www.biorxiv.org/submit-a-manuscript

Biorxiv是生命科学预印本在线存档和分发服务器。它由冷泉港实验室经营，这是一个非营利的研究和教育机构。

Biorxiv is an online archive and distribution service for preprints in the life sciences. It is operated by Cold Spring Harbor Laboratory, a not-for-profit research and educational institution.

一篇文章可以草稿或定稿的形式存放在Biorxiv中，但必须涉及相关科学领域，提交时内容未发表，并且所有作者都同意存放。希望保存手稿的作者必须首先在网站上注册。登记或文章保存不收费。

An article may be deposited in bioRxiv in draft or final form, provided that it concerns a relevant scientific field, the content is unpublished at the time of submission, and all its authors have consented to its deposition. Authors wishing to deposit manuscripts must first register on the site. There is no charge for registration or article deposition.

Biorxiv是技术信息的来源，不应用于分发其他类型的内容，如新闻、产品广告或政策声明。上传到biorxiv的所有文章都要经过一个基本的筛选过程，以筛选攻击性和/或非科学内容，以及可能对健康或生物安全造成威胁的材料。文章在网上发布前不会经过同行评审。冷泉港实验室对其方法、假设、结论或科学质量的认可，并不因其在bioRxiv中的出现而受到暗示。

bioRxiv is a source of technical information and should not be used to distribute other kinds of content such as news, product advertisements, or policy statements. All articles uploaded to bioRxiv undergo a basic screening process for offensive and/or non-scientific content and for material that might pose a health or biosecurity risk. Articles are not peer-reviewed before being posted online. No endorsement of their methods, assumptions, conclusions or scientific quality by Cold Spring Harbor Laboratory is implied by their appearance in bioRxiv.

文章在网上发布前没有排版。作者的手稿要么作为PDF文件提交，要么自动转换为PDF文件。

Articles are not typeset before being posted online. The author’s manuscript is either submitted as, or automatically converted into, a PDF file.

文章按按收到的顺序出现在Biorxiv中。它们可以通过Web界面免费检索。

Articles appear in bioRxiv in the order in which they were received. They are retrievable via the web interface at no charge.

提交格式

SUBMISSION FORMAT

在bioRxiv上存放手稿的最简单方法是上传一份包含文本和任何图表的PDF。补充数据应创建单独的一个或多个文件中。

The simplest way to deposit a manuscript on bioRxiv is to upload a single PDF including the text and any figures/tables. Supplemental data should be created in a separate file or files.

或者，您可以上传一个包含主文本（加上任何表格）的Word文件和单独的图形文件，从中创建一个PDF。一个自动化的PDF转换引擎负责转换，它可以处理许多图形文件格式，包括jpeg、tiff、eps、powerpoint。但是，这些格式不兼容：pict、bitmap、excel、psd。对于这些文件，您需要将其转换为PDF或可接受的文件格式。

Alternatively, you may upload a Word file containing the main text (plus any tables) and separate figure files, from which a single PDF will be created. An automated PDF-conversion engine is responsible for the conversion and it can process many figure file formats, including JPEG, TIFF, EPS, PowerPoint. These formats are not compatible, however: PICT, Bitmap, Excel, PSD. For these files, you will need to convert them to PDF or an acceptable file format.

LaTeX文件应在提交前转换为PDF格式，也可作为补充材料上传。

LaTeX files should be converted to PDF prior to submission; they may also be uploaded as Supplemental Material.

补充材料和数据使用

SUPPLEMENTARY MATERIAL AND DATA USE

作者可以自由添加补充材料，如附加表和视频MPEG文件。然而，大型数据集应该存放在适当的社区数据库中（例如，蛋白质数据库[PDB]，基因库）。（见下文“修订”指南。）

Authors are free to include Supplemental Material such as additional tables and MPEG files. Large data sets, however, should instead be deposited in the appropriate community database (e.g., Protein Data Bank [PDB], GenBank). (See “Revisions” guidelines below.)

作者应遵守所有有关使用和确认数据资源的社区指南（如劳德代尔堡指南），在需要时获得许可，并引用适当的实验室、网站和登记号。

Authors should abide by all relevant community guidelines for use and acknowledgment of data resources (e.g., the Fort Lauderdale guidelines), obtaining permission where required and citing the appropriate laboratory, website, and accession numbers.

分发条款

TERMS OF DISTRIBUTION

在bioRxiv中存放文章后，它是可引用的，因此不能移除。版权归作者所有，作者需要从多个分发/重用选项中进行选择，以使文章可用（CC-BY, CC-BY-NC, CC-BY-ND, CC-BY-NC-ND, CC0或不可重用）。通过在biorxiv上发布，作者明确同意对他们的作品进行文本挖掘（例如，通过搜索引擎或研究人员）。

After an article is deposited in bioRxiv, it is citable and therefore cannot be removed. The copyright remains with the author, who is asked to select from several distribution/reuse options under which to make the article available (CC-BY, CC-BY-NC, CC-BY-ND, CC-BY-NC-ND, CC0, or no reuse). By posting on bioRxiv, authors explicitly consent to text mining of their work (e.g., by search engines or researchers).

Biorxiv保留鉴定和删除任何含有剽窃材料或描述实验工作的工作的权利，这些实验工作不符合使用动物或人类受试者进行研究的相关伦理标准。

bioRxiv reserves the right to identify and remove any articles that contain plagiarized material or describe experimental work that is not performed in accordance with the relevant ethical standards for research using animals or human subjects.

文章类别

ARTICLE CATEGORIES

bioRxiv中的文章分为新结果、证实性结果或矛盾结果。请选择最能描述您的发现的类别。

Articles in bioRxiv are categorized as New Results, Confirmatory Results, or Contradictory Results. Please select the category that best describes your findings.

新的结果最适合描述某个领域的进步的文章。
如果发现大量重复实验并证实先前发表的工作，则应选择证实性结果。
如果研究主要重复先前发表的工作中使用的实验方法，但结果与之相矛盾和/或不支持，则应选择相互矛盾的结果。

New Results is most appropriate for articles that describe an advance in a field.
Confirmatory Results should be selected if the findings largely replicate and confirm previously published work.
Contradictory Results should be selected if the studies largely replicate experimental approaches used in previously published work but the results contradict and/or do not support it.

引用

CITATION

存放在biorxiv中的预印本可以使用其数字对象标识符（doi）引用。

Preprints deposited in bioRxiv can be cited using their digital object identifier (doi).

示例：作者张三，作者李四. 2013. 我的文章标题. bioRxiv doi: 10.1101/123456

Example: Author AN, Author BT. 2013. My article title. bioRxiv doi: 10.1101/123456

修订

REVISIONS

作者可以随时（在期刊上发表之前）通过点击作者区域内的“提交修订”来提交文章的修订版本。新版本将使用与原始提交文件相同的doi，这也将在bioRxiv站点上保持可访问性。如果对任何补充数据有更改，请重新提交论文的所有补充文件。如果补充数据没有更改，则无需重新提交补充文件。

Authors are free to submit a revised version of an article at any time (prior to publication in a journal) by clicking on ‘submit a revision’ within the Author Area. The new version will use the same doi as the original submission, which also will remain accessible on the bioRxiv site. If there are changes to any Supplemental data, resubmit all Supplemental files for the paper. If there are no changes to Supplemental data, there is no need to resubmit Supplemental files.

出版商对预印本的政策列表

LIST OF PUBLISHERS’ PREPRINT POLICIES

大多数研究期刊允许在出版前在预印本服务器（如bioRxiv）上发表文章。可以在维基百科 http://en.wikipedia.org/wiki/List_of_academic_journals_by_preprint_policy 和SHERPA/RoMEO http://www.sherpa.ac.uk/romeo/journalbrowse.php?la=en&fIDnum=|&mode=simple 上找到期刊政策列表。作者应该在发布bioRxiv之前查阅这些列表和其他信息来源。

Most research journals allow posting on preprint servers such as bioRxiv prior to publication. A list of journal policies can be found on Wikipedia and SHERPA/RoMEO. Authors should consult these lists and other sources of information before posting on bioRxiv.

直接从bioRxiv转到期刊或同行评审服务（B2J）

DIRECT TRANSFER FROM BIORXIV TO JOURNALS OR PEER REVIEW SERVICES (B2J)

Biorxiv可以通过直接从Biorxiv传输手稿文件和元数据，节省作者向期刊或同行评审服务提交论文的时间。这意味着作者不必花时间重新加载手稿文件，并在期刊或同行评审服务网站重新输入作者信息。下面列出了当前参与B2J的合作伙伴（滚动查看完整列表）。

bioRxiv can save authors time in submitting papers to journals or peer review services by transmitting their manuscript files and metadata directly from bioRxiv. This means authors do not have to spend time re-loading manuscript files and re-entering author information at the journal or peer review service website. Partners currently participating in B2J are listed below (scroll to view full list).

杂志列表见链接：https://www.biorxiv.org/submit-a-manuscript 右下角，主要包括BMC、Frontiers系列、PLOS系列、PNAS、Science系列等。

提交过程

上述页面点击Submit按扭，或直接访问 https://submit.biorxiv.org/

建新帐号(第一次提交)

可点击 Create a new account创建新用户，输入邮箱，设置密码(要求4-20位间)，这时会往邮箱发送确定邮件。

在邮箱中访问确定链接(无法点击可复制网址访问)，填写详细个人信息，选择领域，完成账号创建。

手稿提交

在作者中心(Author Area)中，点击Submit a new manuscript，按Submission Guide提示填写信息：

• Manuscript Basics选择分类，如New Results，Plant Biology、再填写题目
• Abstract and Author Approvals填写摘要，并作者同意和末发表
• Author list填写作者信息，必须包括邮箱，姓名和单位，可链接ORCID
• Distribution/Reuse Options发布和重用：按个人情况选择，最谨慎选第一个No reuse/adaptation without permission
• Files Metadata是提交格式的说明，推荐Word或PDF，直接继续；
• Manuscript Files提交正文

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